Validation projects

• EU-ECVAM In vitro tests for haematotoxicity: Prevalidation and validation of Colony-Forming Unit - Granulocyte/Macrophage (CFU-GM) Assays for predicting acute neutropenia.
  Coordinator : Prof. A. Pessina (University of Milan, Italy)
  VITO project leader: Dr. R. Van Den Heuvel



• EU-ECVAM Development and prevalidation of in vitro assays for the prediction of thrombocytopenia.
  Coordinator : Prof Dr. Dominique Parrent–Massin (ESMISAB,Brest, France)
  VITO project leader: Dr. R. Van Den Heuvel



• University of Ghent: Prevalidation study of the slug mucosal irritation assay
  Coordinator: : Dr. Els Adriaens
  VITO Project leader: Dr.R.Weltens



• ECVAM Optimisation of cytotoxicity tests for ecotoxicity testing using fish cell lines.(ongoing)
  Technical Responsible at ECVAM: Mrs. Marlies Halder
  VITO project leader: Dr. H. Witters



• EU-project REPROTECT : Prevalidation of ER- and AR- receptor transactivation tests. (ongoing)
  Title: Development of a novel approach in hazard and risk assessment of reproductive toxicity by a combination and application of in vitro, tissue and sensor technologies.
  Coordinator EU-project (scientific): Dr. T. Hartung (ECVAM, Ispra, Italy).
  VITO-project leader: Dr. H. Witters



• 2005-2010: EU-project Sens-it-iv (LSHB-CT-2005-018861) -> ring trials of in vitro tests for chemical-induced sensitization
  Title: Novel Testing Strategies for In Vitro Assessment of Allergens.
  Coordinator EU-project (scientific): Dr. E. Roggen (Novozymes, Bagsvaerd, Denmark)
  VITO-project leader: Dr. I. Nelissen